fentanyl transmucosal and pentobarbital both enhance sedation. Stay away from or Use Alternate Drug. Limit use to patients for whom choice treatment method alternatives are insufficient
Keep an eye on Intently (1)pentobarbital will decrease the level or outcome of levamlodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the extent or outcome of doxorubicin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will decrease the level or result of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
fentanyl transdermal and pentobarbital both raise sedation. Prevent or Use Alternate Drug. Limit use to sufferers for whom option treatment selections are inadequate
Warning when discontinuing CYP3A4 inducers that are coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone could boost and can lead to likely lethal respiratory melancholy.
pentobarbital will lessen the extent or effect of temsirolimus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Drugs which have amount boundaries related to Every single prescription. This restriction ordinarily restrictions the amount of the drug which will be coated.
Contraindicated (1)pentobarbital will decrease the extent or result of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Gals shouldn't choose estradiol valerate/dienogest as their contraceptive when making use of strong CYP3A4 inducers as a consequence of likely decrease in contraceptive efficacy.
Premature infants are especially liable to the depressant effects of barbiturates; if barbiturates are applied for the duration of labor and delivery, resuscitation devices needs to be available
Contraindicated (1)pentobarbital decreases amounts of vandetanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Prevent coadministration with strong CYP3A4 inducers; these drugs minimize exposure to vandetanib by around forty%.
pentobarbital will lessen the level or outcome of larotrectinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital is nembutal a cns depressant will lessen the level or outcome of conjugated estrogens, vaginal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will decrease the extent or impact of buprenorphine, extensive-performing injection by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Patients who transfer to buprenorphine extended-performing injection from transmucosal buprenorphine coadministered with CYP3A4 inducers need to be monitored to guarantee buprenorphine plasma ranges are adequate.